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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 18.48
Human Site: S311 Identified Species: 29.05
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 S311 A K A Q S L P S D Q P V G T F
Chimpanzee Pan troglodytes XP_510301 627 67581 A290 L P Q D P T V A K G A L A G E
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 S311 A K A Q S L P S D Q P V G T F
Dog Lupus familis XP_544614 968 105825 S598 A K A Q S L P S D Q P M G T F
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 S312 A K A Q S L P S E Q P M G T F
Rat Rattus norvegicus Q62829 544 60692 V207 S I Y T R S V V E S I A S P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 L302 A Y P S S G S L H R P P G R P
Chicken Gallus gallus XP_426393 667 74767 S311 S D F P R L I S D A G T P Q R
Frog Xenopus laevis NP_001082100 650 73749 S306 K S S V S K G S S R P Q Q G Q
Zebra Danio Brachydanio rerio XP_001919719 693 77347 V311 S G T S S P L V S G G R H Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 P302 H P H A H P H P H H H Q H L A
Honey Bee Apis mellifera XP_001122147 624 70155 S287 S P V G S I A S Q R P L S Q L
Nematode Worm Caenorhab. elegans Q17850 572 63863 P235 P P A I P D R P A R T L S I Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 D462 M S P T L N T D S S S A N G K
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 E460 V G H E G S F E N P R A P P P
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 0 100 93.3 N.A. 86.6 0 N.A. 26.6 20 20 6.6 N.A. 0 20 6.6 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 13.3 N.A. 33.3 26.6 33.3 13.3 N.A. 0 46.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 0 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 34 7 0 0 7 7 7 7 7 20 7 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 7 0 7 0 7 27 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 0 0 0 7 14 0 0 0 0 0 7 % E
% Phe: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 27 % F
% Gly: 0 14 0 7 7 7 7 0 0 14 14 0 34 20 0 % G
% His: 7 0 14 0 7 0 7 0 14 7 7 0 14 0 0 % H
% Ile: 0 7 0 7 0 7 7 0 0 0 7 0 0 7 0 % I
% Lys: 7 27 0 0 0 7 0 0 7 0 0 0 0 0 7 % K
% Leu: 7 0 0 0 7 34 7 7 0 0 0 20 0 7 7 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 14 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 0 7 0 0 0 7 0 0 % N
% Pro: 7 27 14 7 14 14 27 14 0 7 47 7 14 14 14 % P
% Gln: 0 0 7 27 0 0 0 0 7 27 0 14 7 20 7 % Q
% Arg: 0 0 0 0 14 0 7 0 0 27 7 7 0 7 7 % R
% Ser: 27 14 7 14 54 14 7 47 20 14 7 0 20 0 0 % S
% Thr: 0 0 7 14 0 7 7 0 0 0 7 7 0 27 0 % T
% Val: 7 0 7 7 0 0 14 14 0 0 0 14 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _